Multiple Choice
Which molecule is required for the reduction of 3-phosphoglycerate (3PG) to glyceraldehyde-3-phosphate (G3P) during glycolysis?
33. The Organic Chemistry of Metabolic Pathways
Glycolysis Summary
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Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
In the glycolysis pathway, how many of the six glyceraldehyde-3-phosphate (G3P) molecules produced are used to synthesize one molecule of glucose?
A
Two
B
Four
C
One
D
Three
Verified step by step guidance1
Understand the glycolysis pathway: Glycolysis is the process of breaking down glucose into pyruvate, producing ATP and NADH in the process. It involves several steps and intermediates, including glyceraldehyde-3-phosphate (G3P).
Recognize the role of G3P: In glycolysis, glucose is initially converted into two molecules of G3P. This is a key intermediate in the pathway, which is further processed to eventually form pyruvate.
Consider the reverse process: To synthesize glucose from G3P, you need to consider gluconeogenesis, which is essentially the reverse of glycolysis. This process involves converting G3P back into glucose.
Calculate the requirement: Since glycolysis starts with one glucose molecule and produces two G3P molecules, synthesizing one glucose molecule from G3P would require reversing this process. Therefore, you need two G3P molecules to form one glucose molecule.
Conclude the synthesis: Based on the stoichiometry of the pathway, two molecules of G3P are required to synthesize one molecule of glucose, aligning with the principles of gluconeogenesis.
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