Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

34. Nucleic Acids

Intro to Nucleic Acids

Organic Chemistry

34. Nucleic Acids

Intro to Nucleic Acids

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Multiple Choice

What are the consequences of having pyrimidine dimers in DNA?

They enhance the stability of the DNA double helix.

They facilitate the repair of DNA strands.

They can lead to mutations during DNA replication.

They increase the rate of transcription.

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Verified step by step guidance

Understand that pyrimidine dimers are formed when two adjacent pyrimidine bases, typically thymine, in a DNA strand become covalently bonded due to UV radiation exposure.

Recognize that the formation of pyrimidine dimers distorts the DNA double helix structure, which can interfere with DNA replication and transcription processes.

Acknowledge that the presence of pyrimidine dimers can lead to errors during DNA replication, as the DNA polymerase may insert incorrect bases opposite the dimer, resulting in mutations.

Consider that while cells have repair mechanisms, such as nucleotide excision repair, to remove pyrimidine dimers, these processes are not always perfect and can sometimes lead to mutations if the dimers are not repaired correctly.

Conclude that the primary consequence of pyrimidine dimers is their potential to cause mutations during DNA replication, which can have various biological effects, including contributing to the development of skin cancers like melanoma.