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Multiple Choice
Which of the following reactions involves the addition of a nucleophile to a carbonyl group?
A
Electrophilic aromatic substitution
B
Esterification
C
Nucleophilic acyl substitution
D
Aldol condensation
Verified step by step guidance
1
Identify the functional group involved in each reaction. A carbonyl group is characterized by a carbon atom double-bonded to an oxygen atom (C=O).
Understand the role of a nucleophile. A nucleophile is a species that donates an electron pair to form a chemical bond in reaction.
Examine each reaction type: Electrophilic aromatic substitution involves the substitution of an aromatic hydrogen with an electrophile, not involving a carbonyl group.
Consider esterification, which involves the reaction of an alcohol with a carboxylic acid to form an ester, typically not involving direct nucleophilic addition to a carbonyl group.
Analyze nucleophilic acyl substitution, where a nucleophile attacks the carbonyl carbon, leading to the substitution of a leaving group. This is a classic example of nucleophilic addition to a carbonyl group.