Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

15. Analytical Techniques:IR, NMR, Mass Spect

1H NMR:Spin-Splitting (N + 1) Rule

Organic Chemistry

15. Analytical Techniques:IR, NMR, Mass Spect

1H NMR:Spin-Splitting (N + 1) Rule

Previous problemNext problem

Problem 28

Textbook Question

In Figure 15.34, H_a was assumed to be 'up.' How does the analysis change if we assume instead that H_a is down?

Verified step by step guidance

First, understand the context of the problem: Figure 15.34 likely involves a stereochemical analysis, where the orientation of hydrogen atoms (Hₐ) affects the stereochemistry of the molecule.

Consider the implications of changing the orientation of Hₐ from 'up' to 'down'. This change can affect the stereochemical configuration, such as converting a molecule from R to S configuration or vice versa.

Re-evaluate the stereochemistry of the molecule with Hₐ 'down'. Use the Cahn-Ingold-Prelog priority rules to assign priorities to the substituents around the chiral center. This involves looking at the atomic numbers of the atoms directly attached to the chiral center.

Once priorities are assigned, determine the configuration by tracing a path from the highest priority substituent to the lowest. If the path is clockwise, the configuration is R; if counterclockwise, it is S. Remember to consider the orientation of Hₐ as 'down' in this analysis.

Finally, compare the new configuration with the original assumption of Hₐ 'up'. Discuss how this change affects the overall stereochemistry and any potential reactions or interactions the molecule might undergo.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above

Play a video:

Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Stereochemistry

Stereochemistry involves the study of the spatial arrangement of atoms in molecules and how this affects their chemical behavior. In this context, the orientation of hydrogen (Hₐ) as 'up' or 'down' can significantly impact the molecule's stereochemical configuration, influencing its interactions and reactions.

Newman Projections

Newman projections are a way to visualize the conformation of a molecule by looking along the axis of a bond. Changing the orientation of Hₐ from 'up' to 'down' in a Newman projection can alter the perceived conformation, affecting the analysis of steric interactions and potential energy.

Conformational Analysis

Conformational analysis examines the different shapes that a molecule can adopt due to rotation around single bonds. Assuming Hₐ is 'down' instead of 'up' may lead to different conformers being more or less stable, affecting the molecule's reactivity and properties.

Watch next

Master Splitting without J-values with a bite sized video explanation from Johnny

Start learning

Related Videos

Related Practice

Textbook Question

Why is there no coupling between the a and c protons or between the b and c protons in the cis and trans alkenes shown in Figure 14.20?

<IMAGE>

Textbook Question

Predict the splitting patterns for the signals given by the compounds in Problem 4.

Textbook Question

Predict the splitting patterns for the signals given by the compounds in Problem 4.

c. CH₂=CCl₂

Textbook Question

Label each set of chemically equivalent protons, using a for the set that will be at the lowest frequency in the ¹H NMR spectrum, b for the next lowest, and so on. Indicate the multiplicity of each signal.

Textbook Question

Though Figure 15.34 was concerned with the appearance of H_a, how would H_b appear in the spectrum?

Textbook Question

Every number in Pascal’s triangle is the sum of the two numbers above it. Given this, fill in the missing numbers.

Textbook Question

Indicate the number of signals and the multiplicity of each signal in the 1H NMR spectrum of each of the following compounds:

c. ClCH₂CH₂CH₂Cl

Textbook Question

Indicate the number of signals and the multiplicity of each signal in the 1H NMR spectrum of each of the following compounds:

a. CH₃CH₂CH₂CH₂CH₂CH₃

Show more practices

Download the Mobile app

Privacy

Do not sell my personal information

Accessibility

Patent notice

Sitemap

In Figure 15.34, Ha was assumed to be 'up.' How does the analysis change if we assume instead that Ha is down?

Key Concepts

Stereochemistry

Newman Projections

Conformational Analysis

Watch next

In Figure 15.34, H_a was assumed to be 'up.' How does the analysis change if we assume instead that H_a is down?