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Multiple Choice
Polyenes bind to which of the following parts of fungi?
A
DNA in the nucleus
B
Ribosomes in the cytoplasm
C
Chitin in the cell wall
D
Ergosterol in the cell membrane
Verified step by step guidance
1
Understand the structure of fungi: Fungi have a cell membrane that contains a unique sterol called ergosterol, which is similar to cholesterol in animal cells.
Identify the role of polyenes: Polyenes are a class of antifungal compounds that target the cell membrane of fungi.
Recognize the mechanism of action: Polyenes bind specifically to ergosterol in the fungal cell membrane, disrupting its structure and function.
Consider the options given: Evaluate each option based on the known mechanism of polyenes. DNA, ribosomes, and chitin are not the primary targets of polyenes.
Conclude with the correct target: Based on the mechanism of action, polyenes bind to ergosterol in the cell membrane of fungi, leading to increased membrane permeability and cell death.