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Multiple Choice
Which of the following functional groups is most likely to be affected by a mutation in the iron regulatory protein (IRP) that prevents it from binding to iron?
A
Iron-sulfur cluster
B
Carboxyl group
C
Hydroxyl group
D
Sulfhydryl group
Verified step by step guidance
1
Understand the role of the iron regulatory protein (IRP) in cellular processes. IRPs are involved in the regulation of iron metabolism by binding to iron-sulfur clusters.
Recognize that an iron-sulfur cluster is a type of prosthetic group that contains iron and sulfur atoms. These clusters are crucial for the function of various proteins, including IRPs.
Consider the impact of a mutation in the IRP that prevents it from binding to iron. Such a mutation would likely affect the iron-sulfur cluster, as this is the component of the IRP that directly interacts with iron.
Evaluate the other functional groups listed: carboxyl group, hydroxyl group, and sulfhydryl group. These groups do not typically interact with iron in the context of IRPs, making them less likely to be affected by a mutation that impacts iron binding.
Conclude that the iron-sulfur cluster is the functional group most likely to be affected by a mutation in the IRP that prevents it from binding to iron, as it is directly involved in the protein's iron-binding capability.