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Multiple Choice
In the context of organic chemistry reactions, which type of mutation in a molecule's structure is likely to have the greatest effect on its reactivity?
A
Deletion mutation
B
Addition mutation
C
Conformational mutation
D
Substitution mutation
Verified step by step guidance
1
Understand the types of mutations mentioned: Deletion, Addition, Conformational, and Substitution mutations. Each involves a change in the molecular structure that can affect reactivity.
Deletion mutation involves the removal of an atom or group from the molecule, potentially altering its reactivity by changing the functional groups or steric hindrance.
Addition mutation involves adding an atom or group to the molecule, which can introduce new functional groups or change the steric environment, affecting reactivity.
Conformational mutation refers to changes in the spatial arrangement of atoms within a molecule without altering the connectivity. This can significantly affect reactivity by altering the molecule's shape and how it interacts with other molecules.
Substitution mutation involves replacing one atom or group in the molecule with another, which can change the electronic properties and reactivity by introducing different functional groups or altering the molecule's polarity.