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Multiple Choice
Which of the following organic chemistry reactions is most likely to result in the formation of an oncogene?
A
Esterification of alcohols
B
Alkylation of DNA bases
C
Hydrolysis of esters
D
Hydrogenation of alkenes
Verified step by step guidance
1
Understand the context: Oncogenes are genes that have the potential to cause cancer. They are often activated by mutations or increased expression due to chemical modifications.
Identify the reaction types: The problem lists four types of reactions: esterification of alcohols, alkylation of DNA bases, hydrolysis of esters, and hydrogenation of alkenes.
Consider the impact of each reaction on DNA: Alkylation of DNA bases can lead to mutations by adding alkyl groups to the DNA, potentially causing mispairing during replication.
Evaluate the other reactions: Esterification, hydrolysis, and hydrogenation are less likely to directly interact with DNA in a way that would lead to oncogene formation.
Conclude that alkylation of DNA bases is the most likely reaction to result in the formation of an oncogene due to its potential to cause mutations in the genetic material.