Multiple Choice
In the context of organic chemistry reactions, which type of light is most effectively absorbed by chlorophyll in plants during photosynthesis?
3. Acids and Bases
Organic Chemistry Reactions
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Which statement about signaling through G-protein coupled receptors (GPCRs) is correct?
A
GPCRs directly phosphorylate proteins to initiate signaling.
B
GPCRs activate G-proteins by facilitating the exchange of GDP for GTP.
C
GPCRs are ion channels that allow the passage of ions across the membrane.
D
GPCRs require dimerization to become active.
Verified step by step guidance1
Understand the role of G-protein coupled receptors (GPCRs) in cellular signaling. GPCRs are a large family of receptors that detect molecules outside the cell and activate internal signal transduction pathways.
Recognize that GPCRs do not directly phosphorylate proteins. Instead, they activate G-proteins, which are intracellular proteins that relay signals from the activated receptor to other targets within the cell.
Learn about the mechanism of G-protein activation. When a GPCR binds its ligand, it undergoes a conformational change that facilitates the exchange of GDP for GTP on the G-protein, thus activating it.
Clarify that GPCRs are not ion channels. While some receptors are ion channels, GPCRs function through the activation of G-proteins rather than directly allowing ions to pass through the membrane.
Understand that GPCRs do not require dimerization to become active. Unlike some receptors that need to form dimers, GPCRs can activate G-proteins as monomers upon ligand binding.
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