Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

30. Peptides and Proteins

Peptides

Organic Chemistry

30. Peptides and Proteins

Peptides

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Multiple Choice

Which bond is a peptide bond in a polypeptide chain?

The bond between the nitrogen of one amino acid and the alpha carbon of the next

The bond between the side chain of one amino acid and the side chain of another

The bond between the alpha carbon and the side chain of an amino acid

The bond between the carbonyl carbon of one amino acid and the nitrogen of the next amino acid

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Verified step by step guidance

Understand the structure of amino acids: Each amino acid has a central alpha carbon (C_α), an amino group (-NH₂), a carboxyl group (-COOH), and a variable side chain (R group).

Learn how peptide bonds form: A peptide bond is a covalent bond that forms between the carboxyl group of one amino acid and the amino group of another. This occurs through a dehydration synthesis reaction, where a molecule of water is removed.

Identify the specific atoms involved in a peptide bond: The peptide bond specifically forms between the carbonyl carbon (C=O) of the carboxyl group of one amino acid and the nitrogen (N) of the amino group of the next amino acid.

Visualize the peptide bond in a polypeptide chain: In a polypeptide chain, the repeating unit is the backbone, which consists of the sequence -N-C_α-C(=O)-. The peptide bond is the linkage between the carbonyl carbon and the nitrogen in this sequence.

Clarify the correct answer: The peptide bond is the bond between the carbonyl carbon of one amino acid and the nitrogen of the next amino acid, not involving the side chains or the alpha carbon directly.