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Multiple Choice
Which amino acid is most soluble in water?
A
Glycine
B
Tryptophan
C
Phenylalanine
D
Leucine
Verified step by step guidance
1
Identify the structural features of each amino acid: Glycine, Tryptophan, Phenylalanine, and Leucine.
Consider the polarity of each amino acid. Polar amino acids are generally more soluble in water due to their ability to form hydrogen bonds with water molecules.
Glycine is the simplest amino acid with a hydrogen as its side chain, making it highly polar and thus more soluble in water.
Tryptophan, Phenylalanine, and Leucine have larger, non-polar side chains (aromatic rings and aliphatic chains), which decrease their solubility in water compared to Glycine.
Conclude that Glycine, with its small and polar side chain, is the most soluble in water among the given options.