Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

22. Carboxylic Acid Derivatives: NAS

Carboxylation

Organic Chemistry

22. Carboxylic Acid Derivatives: NAS

Carboxylation

Previous problemNext problem

6:02 minutes

Problem 73b

Textbook Question

Using the given starting material, any necessary inorganic reagents, and any carbon-containing compounds with no more than two carbons, indicate how the following syntheses could be carried out:
b.

Verified step by step guidance

Analyze the target molecule and the starting material to identify the functional groups present and the changes required to convert the starting material into the target molecule. This includes identifying any new bonds formed or broken, as well as any rearrangements or functional group transformations.

Determine the sequence of reactions needed to achieve the transformation. Consider the use of reagents that can introduce or modify functional groups, such as oxidizing agents, reducing agents, or reagents for substitution or elimination reactions. Ensure that all carbon-containing reagents used have no more than two carbons.

Plan the synthesis step-by-step, starting with the given starting material. For each step, specify the reagent(s) and reaction conditions required to achieve the desired transformation. For example, if a hydroxyl group needs to be converted to a carbonyl group, consider using an oxidizing agent like PCC (Pyridinium chlorochromate).

Verify that each intermediate in the synthesis is stable and can be isolated or carried forward to the next step. Ensure that the reaction conditions for each step are compatible with the functional groups present in the molecule.

Double-check the overall synthesis to confirm that the target molecule is obtained, and that all reagents and intermediates comply with the given constraints (e.g., carbon-containing compounds with no more than two carbons).

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above

Video duration:

Play a video:

Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Organic Synthesis

Organic synthesis is the process of constructing organic compounds through chemical reactions. It involves the strategic selection of starting materials, reagents, and reaction conditions to achieve the desired product. Understanding the principles of organic synthesis is crucial for designing pathways that efficiently convert simple molecules into more complex structures.

Reagents and Their Functions

In organic chemistry, reagents are substances that are added to a reaction to cause a chemical change. Different reagents can facilitate various types of reactions, such as oxidation, reduction, or substitution. Knowing the role of specific inorganic reagents and their compatibility with carbon-containing compounds is essential for successful synthesis.

Functional Groups

Functional groups are specific groups of atoms within molecules that are responsible for the characteristic chemical reactions of those molecules. Identifying functional groups in both starting materials and potential products is vital for predicting reactivity and determining the appropriate synthetic routes. Understanding how these groups interact can guide the selection of reagents and conditions for synthesis.

Watch next

Master Carbonation of Grignard Reagents with a bite sized video explanation from Johnny

Start learning