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Multiple Choice
Which of the following reactions is commonly used in the synthesis of monoclonal antibodies?
A
Esterification
B
Hydrogenation
C
Amide bond formation
D
Diels-Alder reaction
Verified step by step guidance
1
Understand the context: Monoclonal antibodies are proteins, and their synthesis involves forming peptide bonds, which are a type of amide bond.
Recognize that esterification involves forming an ester from an alcohol and an acid, which is not relevant to protein synthesis.
Identify that hydrogenation is a reaction that adds hydrogen to unsaturated bonds, typically in organic compounds, and is not involved in forming peptide bonds.
Recall that the Diels-Alder reaction is a cycloaddition reaction used to form cyclic compounds, not relevant to peptide or protein synthesis.
Conclude that amide bond formation is the key reaction in synthesizing proteins, including monoclonal antibodies, as it forms the peptide bonds between amino acids.