Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

3. Acids and Bases

Organic Chemistry Reactions

Organic Chemistry

3. Acids and Bases

Organic Chemistry Reactions

Previous problemNext problem

Struggling with Organic Chemistry?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

Which of the following reactions is most commonly used in the synthesis of antibiotics to combat antibiotic resistance?

Amide bond formation

Friedel-Crafts acylation

Diels-Alder reaction

Aldol condensation

Previous problemNext problem

Verified step by step guidance

Understand the context: Antibiotics often contain amide bonds, which are crucial for their biological activity. Amide bond formation is a key reaction in the synthesis of many antibiotics.

Review the reaction types: Amide bond formation involves the reaction between a carboxylic acid (or its derivative) and an amine to form an amide. This is a fundamental reaction in organic chemistry, especially in peptide and protein synthesis.

Consider the other reactions: Friedel-Crafts acylation is used to introduce acyl groups into aromatic rings, Diels-Alder reaction is a cycloaddition used to form six-membered rings, and Aldol condensation is used to form carbon-carbon bonds between aldehydes or ketones.

Evaluate the relevance: While Friedel-Crafts, Diels-Alder, and Aldol reactions are important, they are not typically associated with the direct synthesis of antibiotics, which often require the formation of amide bonds.

Conclude the analysis: Given the importance of amide bonds in the structure of many antibiotics, amide bond formation is the most relevant reaction for synthesizing antibiotics to combat antibiotic resistance.