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Multiple Choice
Which of the following reactions involves the use of a Grignard reagent to form a new carbon-carbon bond?
A
Friedel-Crafts acylation
B
Aldol condensation
C
Wittig reaction
D
Grignard reaction
Verified step by step guidance
1
Understand the role of Grignard reagents: Grignard reagents are organomagnesium compounds typically represented as RMgX, where R is an organic group and X is a halogen. They are used to form new carbon-carbon bonds by reacting with electrophiles.
Identify the reaction type: The Grignard reaction specifically involves the use of Grignard reagents to form new carbon-carbon bonds. This is a key characteristic that distinguishes it from other reactions.
Compare with other reactions: Friedel-Crafts acylation involves the formation of carbon-carbon bonds but uses a different mechanism involving acyl chlorides and Lewis acids. Aldol condensation involves the formation of carbon-carbon bonds between aldehydes or ketones, but does not use Grignard reagents. The Wittig reaction forms carbon-carbon double bonds using phosphonium ylides, not Grignard reagents.
Recognize the Grignard reaction: In the Grignard reaction, the Grignard reagent acts as a nucleophile, attacking electrophilic carbon atoms, such as those in carbonyl groups, to form new carbon-carbon bonds.
Conclude the identification: Based on the characteristics and mechanisms of the reactions listed, the Grignard reaction is the one that specifically involves the use of Grignard reagents to form new carbon-carbon bonds.