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Multiple Choice
What is the name of the reaction which couples a carbon bound to a leaving group with a carbon bound to a B(OH)2 group?
A
Stille
B
Suzuki
C
Negishi
D
Sonogashira
Verified step by step guidance
1
Identify the type of reaction: The problem describes a coupling reaction involving a carbon bound to a leaving group and a carbon bound to a B(OH)₂ group.
Recognize the key components: The presence of a B(OH)₂ group indicates the involvement of an organoboron compound, which is characteristic of Suzuki coupling reactions.
Understand the mechanism: Suzuki reactions typically involve the palladium-catalyzed cross-coupling of organoboron compounds with halides or pseudohalides, forming a new carbon-carbon bond.
Differentiate from other reactions: Compare with other coupling reactions like Stille (involving organotin compounds), Negishi (involving organozinc compounds), and Sonogashira (involving alkynes and copper co-catalyst).
Conclude the identification: Based on the components and mechanism, the reaction described is a Suzuki coupling reaction.