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1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

8. Elimination Reactions

Solvents

Organic Chemistry

8. Elimination Reactions

Solvents

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Multiple Choice

Which of the following is the best base to use in an E2 reaction?

H₂O

The figure illustrates the structure of a molecule. A 3-carbon alkane chain is depicted as a line structure using 2 zigzag lines. C 2 is single bonded to C H 3 on the lower left in the form of a line and single bonded to O H on the lower right.

The figure illustrates the structure of a molecule labelled L D A. A 1 N and 4 C heteronuclear alkane chain is depicted as a line structure using 4 zigzag lines. N bound to L i occupies the third position. C 2 is single bonded to C H 3 on the left in the form of a line. C 3 is single bonded to C H 3 on the left in the form of a line.

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Verified step by step guidance

Understand the E2 reaction mechanism: E2 reactions are bimolecular elimination reactions where a base removes a proton from a substrate, leading to the formation of a double bond.

Identify the characteristics of a good base for E2 reactions: A strong base is typically required to effectively abstract a proton from the substrate, facilitating the elimination process.

Analyze the provided bases: The images show different chemical structures that can act as bases. Evaluate their strength and steric hindrance.

Consider the steric hindrance: Bulky bases are often preferred in E2 reactions because they can effectively abstract protons without causing substitution reactions.

Evaluate the base strength: Compare the basicity of the given compounds. Lithium diisopropylamide (LDA) is a strong, non-nucleophilic base, making it suitable for E2 reactions.