Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

34. Nucleic Acids

Intro to Nucleic Acids

Organic Chemistry

34. Nucleic Acids

Intro to Nucleic Acids

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Multiple Choice

Which of the following is not one of the main differences between DNA and RNA?

DNA is more stable than RNA due to the absence of a hydroxyl group on the 2' carbon.

DNA uses uracil as a base, while RNA uses thymine.

DNA contains deoxyribose sugar, while RNA contains ribose sugar.

DNA is typically double-stranded, whereas RNA is usually single-stranded.

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Verified step by step guidance

Begin by identifying the structural differences between DNA and RNA. DNA contains deoxyribose sugar, while RNA contains ribose sugar. This difference is due to the presence of a hydroxyl group on the 2' carbon in ribose, which is absent in deoxyribose.

Consider the stability of DNA versus RNA. DNA is more stable than RNA because the absence of the hydroxyl group on the 2' carbon in DNA reduces its reactivity, making it less prone to hydrolysis.

Examine the base pairing differences. DNA uses thymine as one of its bases, while RNA uses uracil. This is a key distinction in the nucleotide composition of these molecules.

Analyze the structural form of these nucleic acids. DNA is typically double-stranded, forming a double helix, whereas RNA is usually single-stranded, allowing it to fold into various shapes and perform different functions.

Review the options provided in the problem. The statement 'DNA uses uracil as a base, while RNA uses thymine' is incorrect because it reverses the actual base usage in DNA and RNA. Therefore, this is not a main difference between DNA and RNA.