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Multiple Choice
In the process of reverse transcription, what does reverse transcriptase use as a template to synthesize DNA?
A
DNA
B
RNA
C
Protein
D
Lipids
Verified step by step guidance
1
Understand the role of reverse transcriptase: Reverse transcriptase is an enzyme that synthesizes DNA from an RNA template. This process is crucial in the life cycle of retroviruses, such as HIV.
Identify the substrates involved: Reverse transcriptase uses RNA as the template to synthesize complementary DNA (cDNA). This is the reverse of the usual transcription process, where DNA is used to make RNA.
Clarify the process: During reverse transcription, the enzyme binds to the RNA template and begins synthesizing a complementary DNA strand by adding deoxyribonucleotides that are complementary to the RNA bases.
Recognize the significance: This process is essential for the integration of viral genetic material into the host genome, allowing the virus to replicate within the host cell.
Conclude with the correct template: Therefore, the correct template used by reverse transcriptase to synthesize DNA is RNA.