Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

33. The Organic Chemistry of Metabolic Pathways

ATP and Energy

Organic Chemistry

33. The Organic Chemistry of Metabolic Pathways

ATP and Energy

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Multiple Choice

What evidence suggests that the hydrolysis of ATP is an exergonic reaction?

The hydrolysis of ATP is an endergonic reaction.

The hydrolysis of ATP releases a large amount of free energy.

The hydrolysis of ATP requires an input of energy to proceed.

The hydrolysis of ATP results in the formation of ADP and inorganic phosphate.

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Verified step by step guidance

Understand the concept of exergonic reactions: Exergonic reactions are those that release energy to the surroundings. This is typically indicated by a negative change in Gibbs free energy (ΔG).

Identify the chemical process: The hydrolysis of ATP involves breaking the bond between the terminal phosphate group and the rest of the ATP molecule, resulting in the formation of ADP and inorganic phosphate (Pi).

Analyze the energy change: During ATP hydrolysis, the energy stored in the high-energy phosphate bond is released, which is why this process is considered exergonic. The release of energy is a key indicator of an exergonic reaction.

Consider the thermodynamic evidence: The hydrolysis of ATP has a negative ΔG value, which quantitatively supports the idea that it is an exergonic reaction. This negative ΔG indicates that the reaction proceeds spontaneously and releases energy.

Evaluate the biological significance: In biological systems, the energy released from ATP hydrolysis is used to drive various endergonic processes, such as muscle contraction and active transport, further supporting the exergonic nature of ATP hydrolysis.