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Multiple Choice
Which enzyme covalently links nucleotides together during the formation of a nucleic acid strand?
A
DNA ligase
B
RNA polymerase
C
Topoisomerase
D
Helicase
Verified step by step guidance
1
Identify the role of each enzyme listed in the options to understand their functions in nucleic acid metabolism.
DNA ligase is an enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It is crucial in DNA replication and repair.
RNA polymerase is responsible for synthesizing RNA from a DNA template during transcription, not for linking nucleotides in a DNA strand.
Topoisomerase is involved in the overwinding or underwinding of DNA, helping to relieve strain during DNA replication and transcription, but it does not link nucleotides together.
Helicase unwinds the DNA double helix, separating the two strands to allow replication or transcription to occur, but it does not covalently link nucleotides.