Predict the major, organic product for the following reaction. <img src="https://media.pearsoncmg.com/ph/esm/ecs_mullins_organic1e/msa/content/practice-test/img/Ch26_Q06_QT.jpg" alt="The figure illustrates a reaction in which the product has to be determined. The reaction contains two reactants. The first reactant has the following structure: A 2-carbon alkane chain is depicted as a line structure using 1 line. C 1 is single bonded to N H 2 on the upper left. C 1 is dash bonded below to C 1 of a 3-carbon alkane chain depicted as a line structure using 2 zigzag lines. C 2 of the 3-carbon chain is single bonded to C H 3 below in the form of a line. C 2 of the 2-carbon alkane chain is double bonded to O above and single bonded to O H on the lower right. The second reactant written over the reaction arrow has the following structure: A 1 O and 4 C heteronuclear alkane chain is depicted as a line structure using 4 zigzag lines. O occupies the third position. C 2 and C 3 are each double bonded to O above. E t 3 N is written under the reaction arrow." />

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1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

22. Carboxylic Acid Derivatives: NAS

Nucleophilic Acyl Substitution

Organic Chemistry

22. Carboxylic Acid Derivatives: NAS

Nucleophilic Acyl Substitution

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Multiple Choice

Predict the major, organic product for the following reaction.

The figure illustrates the structure of a molecule. A 1 N and 4 C heteronuclear alkane chain is depicted as a line structure using 4 zigzag lines. N bound to H occupies the third position. C 2 is double bonded to O below. C 3 is dash bonded below to C 1 of a 3-carbon alkane chain depicted as a line structure using 2 zigzag lines. C 2 of the 3-carbon chain is single bonded to C H 3 below in the form of a line. C 4 is double bonded to O above and single bonded to O H on the lower right.

The figure illustrates the structure of a molecule. A central C atom is single bonded to N H 2 on the upper left and single bonded on the upper right to a second central C atom in the form of a line. The second central C atom is double bonded to O above and single bonded to O H on the lower right. The first central C atom is single bonded to C H 2 on the lower left in the form of a line. C H 2 is single bonded on the left to C 2 of a 3-carbon alkane chain depicted as a line structure using 2 zigzag lines. The first central C atom is single bonded on the lower right to a third central C atom in the form of a line. The third central C atom is double bonded to O on the right and single bonded to C H 3 on the lower left in the form of a line.

The figure illustrates the structure of a molecule. A 1 O, 1 N, and 6 C heteronuclear alkane chain is depicted as a line structure using 7 zigzag lines. N bound to H occupies the third position, and O occupies the sixth position. C 2 is double bonded to O below. C 3 is dash bonded below to C 1 of a 3-carbon alkane chain depicted as a line structure using 2 zigzag lines. C 2 of the 3-carbon chain is single bonded to C H 3 below in the form of a line. C 4 and C 5 are each double bonded to O above.

The figure illustrates the structure of a molecule. A 1 O and 4 C heteronuclear alkane chain is depicted as a line structure using 4 zigzag lines. O occupies the third position. C 1 is single bonded to N H 2 on the upper left. C 1 is dash bonded below to C 1 of a 3-carbon alkane chain depicted as a line structure using 2 zigzag lines. C 2 of the 3-carbon chain is single bonded to C H 3 below in the form of a line. C 2 and C 3 of the heteronuclear alkane chain are each double bonded to O above.

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Verified step by step guidance

Identify the functional groups in the reactants: The starting material contains an amino group (NH2) and a carboxylic acid group (COOH). The reagent is an anhydride, which can react with nucleophiles.

Recognize the type of reaction: This is an acylation reaction where the amino group can act as a nucleophile and attack the carbonyl carbon of the anhydride.

Consider the role of the base (Et3N): Triethylamine (Et3N) is a base that can deprotonate the amino group, increasing its nucleophilicity and facilitating the nucleophilic attack on the anhydride.

Predict the reaction mechanism: The deprotonated amino group attacks the carbonyl carbon of the anhydride, leading to the formation of an amide bond and the release of a carboxylate ion.

Determine the major product: The major product will be an amide formed by the acylation of the amino group, with the carboxylic acid group remaining unchanged.