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Multiple Choice
How do steroid hormones differ from polypeptide hormones and most amino-acid-derived hormones in terms of their mechanism of action?
A
Steroid hormones are water-soluble and travel freely in the bloodstream.
B
Steroid hormones pass through cell membranes and bind to intracellular receptors.
C
Steroid hormones are derived from amino acids and act through ion channels.
D
Steroid hormones bind to cell surface receptors and activate second messenger systems.
Verified step by step guidance
1
Understand the nature of steroid hormones: Steroid hormones are lipophilic (fat-soluble) molecules derived from cholesterol, which allows them to easily pass through the lipid bilayer of cell membranes.
Recognize the mechanism of action for steroid hormones: Once inside the cell, steroid hormones bind to specific intracellular receptors located in the cytoplasm or nucleus.
Compare with polypeptide and amino-acid-derived hormones: These hormones are generally hydrophilic (water-soluble) and cannot pass through the cell membrane. Instead, they bind to cell surface receptors.
Explore the action of polypeptide and amino-acid-derived hormones: Upon binding to cell surface receptors, these hormones typically activate second messenger systems, such as cyclic AMP (cAMP), to relay the signal inside the cell.
Summarize the key difference: The primary distinction is that steroid hormones directly interact with intracellular receptors, while polypeptide and amino-acid-derived hormones rely on cell surface receptors and second messenger pathways to exert their effects.