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Multiple Choice
What is the major product of the reaction?
A
B
C
Both A and B
D
None of these
Verified step by step guidance
1
Identify the starting material: The structure provided is 2-chlorobutane, which is a secondary alkyl halide.
Recognize the reagent: LiTMP (Lithium tetramethylpiperidide) is a strong, non-nucleophilic base used for deprotonation.
Determine the site of deprotonation: LiTMP will abstract a proton from the most accessible position, typically the least sterically hindered one adjacent to the halide, forming a carbanion.
Consider the formation of the carbanion: The carbanion formed will undergo elimination, resulting in the formation of an alkene. This is an E2 elimination reaction.
Predict the major product: The major product will be the more substituted alkene due to Zaitsev's rule, which states that the more substituted alkene is favored in elimination reactions.