Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

29. Amino Acids

Proteins and Amino Acids

Organic Chemistry

29. Amino Acids

Proteins and Amino Acids

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Multiple Choice

In a pulse-chase experiment, which type of proteins are typically radioactively labeled to study their synthesis and degradation?

Structural proteins

Membrane proteins

Secretory proteins

Enzymatic proteins

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Verified step by step guidance

Understand the concept of a pulse-chase experiment: This technique is used to study the synthesis and degradation of proteins within cells. It involves 'pulsing' cells with a radioactive amino acid to label newly synthesized proteins, followed by a 'chase' with non-radioactive amino acids to track the fate of these proteins over time.

Identify the types of proteins involved: In the context of a pulse-chase experiment, secretory proteins are often the focus. These proteins are synthesized in the endoplasmic reticulum and transported through the Golgi apparatus to be secreted outside the cell.

Consider the cellular pathway: Secretory proteins follow a specific pathway that includes synthesis in the rough endoplasmic reticulum, modification in the Golgi apparatus, and eventual secretion outside the cell. This makes them ideal candidates for studying synthesis and degradation using pulse-chase experiments.

Evaluate the labeling process: During the 'pulse' phase, secretory proteins are labeled with radioactive amino acids as they are synthesized. This allows researchers to track their movement and degradation over time during the 'chase' phase.

Conclude why secretory proteins are chosen: Secretory proteins are chosen for pulse-chase experiments because their synthesis and transport pathways are well-defined, making it easier to study their life cycle and understand cellular processes related to protein synthesis and degradation.