Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

29. Amino Acids

Proteins and Amino Acids

Organic Chemistry

29. Amino Acids

Proteins and Amino Acids

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Multiple Choice

Which type of chemical modification of a protein is known to have the widest variety of activities?

Acetylation

Methylation

Glycosylation

Phosphorylation

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Verified step by step guidance

Understand the concept of protein modification: Protein modifications are chemical changes to proteins that can alter their function, activity, or localization. These modifications are crucial for regulating cellular processes.

Identify the types of protein modifications: Common types include acetylation, methylation, glycosylation, and phosphorylation. Each has distinct roles and effects on protein function.

Explore phosphorylation: Phosphorylation involves the addition of a phosphate group (PO₄³⁻) to a protein, typically on serine, threonine, or tyrosine residues. This modification can activate or deactivate enzymes, alter protein interactions, and affect cellular signaling pathways.

Compare the variety of activities: Phosphorylation is known for its versatility in regulating a wide range of cellular activities, including metabolism, cell division, and signal transduction. It is a reversible modification, allowing dynamic control of protein function.

Conclude why phosphorylation is the correct answer: Due to its ability to influence numerous cellular processes and its role in signaling pathways, phosphorylation is recognized as having the widest variety of activities among protein modifications.