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Multiple Choice
What type of bond attaches the phosphate group of one nucleotide to the sugar of another nucleotide in a nucleic acid strand?
A
Phosphodiester bond
B
Hydrogen bond
C
Ionic bond
D
Glycosidic bond
Verified step by step guidance
1
Understand the structure of nucleic acids: Nucleic acids, such as DNA and RNA, are composed of long chains of nucleotides. Each nucleotide consists of a sugar, a phosphate group, and a nitrogenous base.
Identify the components involved in the bond formation: In a nucleic acid strand, the phosphate group of one nucleotide is linked to the sugar of the next nucleotide.
Recognize the type of bond: The bond that forms between the phosphate group of one nucleotide and the sugar of another is known as a phosphodiester bond.
Explain the phosphodiester bond: A phosphodiester bond is a covalent bond that involves the esterification of the phosphate group with the hydroxyl group of the sugar molecule, specifically the 3' hydroxyl group of one sugar and the 5' phosphate group of the next sugar.
Differentiate from other bond types: Clarify that hydrogen bonds typically occur between nitrogenous bases, ionic bonds involve electrostatic attraction between charged ions, and glycosidic bonds connect sugars to other molecules, such as in carbohydrates.