Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

34. Nucleic Acids

Intro to Nucleic Acids

Organic Chemistry

34. Nucleic Acids

Intro to Nucleic Acids

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Multiple Choice

What is the role of Dicer in RNA-induced gene silencing?

Dicer cleaves double-stranded RNA into small interfering RNAs (siRNAs).

Dicer phosphorylates RNA molecules to activate them.

Dicer binds to mRNA to prevent its translation.

Dicer integrates siRNAs into the RNA-induced silencing complex (RISC).

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Verified step by step guidance

Understand the concept of RNA-induced gene silencing: This is a biological process where RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules.

Learn about Dicer: Dicer is an enzyme that plays a crucial role in the RNA interference (RNAi) pathway. It is responsible for processing double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs).

Explore the function of Dicer: Dicer cleaves long dsRNA molecules into siRNAs, which are typically 21-25 nucleotides in length. This cleavage is essential for the formation of siRNAs that guide the RNA-induced silencing complex (RISC) to target specific mRNA for degradation.

Clarify the role of siRNAs: Once produced by Dicer, siRNAs are incorporated into the RISC. The siRNA-RISC complex then binds to complementary mRNA sequences, leading to mRNA cleavage and subsequent gene silencing.

Distinguish between the options: The correct role of Dicer is to cleave dsRNA into siRNAs, not to phosphorylate RNA, bind directly to mRNA, or integrate siRNAs into RISC. Its primary function is the generation of siRNAs from dsRNA.