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Multiple Choice
In the context of organic chemistry reactions, which of the following processes involves the transfer of an acyl group to a nucleophile?
A
Esterification
B
Acylation
C
Hydrogenation
D
Hydrolysis
Verified step by step guidance
1
Identify the key terms in the problem: 'acyl group', 'nucleophile', and the processes listed (Esterification, Acylation, Hydrogenation, Hydrolysis).
Understand the concept of an acyl group: An acyl group is a functional group derived from a carboxylic acid by removal of a hydroxyl group, typically represented as RCO- where R is an organic substituent.
Define the term 'nucleophile': A nucleophile is a chemical species that donates an electron pair to form a chemical bond in reaction. Nucleophiles are typically rich in electrons and seek positively charged or electron-deficient sites.
Analyze each process:
- Esterification involves the reaction of an alcohol with a carboxylic acid to form an ester and water, not directly involving a nucleophile receiving an acyl group.
- Acylation involves the transfer of an acyl group to a nucleophile, typically in reactions such as Friedel-Crafts acylation.
- Hydrogenation involves the addition of hydrogen, not related to acyl group transfer.
- Hydrolysis involves breaking bonds with the addition of water, not specifically transferring an acyl group to a nucleophile.
Conclude that Acylation is the process that involves the transfer of an acyl group to a nucleophile, as it directly involves the nucleophilic attack on an acyl compound, resulting in the transfer of the acyl group.