Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

3. Acids and Bases

Acids and Bases

Organic Chemistry

3. Acids and Bases

Acids and Bases

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Multiple Choice

Which of the following statements about the acidity of phosphofructokinase regulation is false?

Phosphofructokinase activity is unaffected by changes in pH.

Phosphofructokinase activity is enhanced by high levels of AMP.

Phosphofructokinase activity is regulated by citrate levels.

Phosphofructokinase activity is inhibited by high levels of ATP.

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Verified step by step guidance

Understand the role of phosphofructokinase (PFK) in glycolysis: PFK is a key regulatory enzyme in the glycolytic pathway, controlling the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate.

Review the factors that regulate PFK activity: PFK is regulated by several factors, including ATP, AMP, citrate, and pH levels. These factors influence the enzyme's activity by altering its conformation and affinity for substrates.

Analyze the effect of ATP on PFK: High levels of ATP inhibit PFK activity, as ATP serves as an allosteric inhibitor, signaling that the cell has sufficient energy and slowing down glycolysis.

Consider the impact of AMP on PFK: High levels of AMP enhance PFK activity, as AMP acts as an allosteric activator, indicating low energy levels and promoting glycolysis to generate more ATP.

Evaluate the statement about pH: Changes in pH can affect enzyme activity, including PFK. Therefore, the statement that PFK activity is unaffected by changes in pH is false, as pH can influence enzyme structure and function.