Multiple Choice
Which reaction produces a ketone body with an alcohol functional group? Draw the ketone body.
24. Lipid Metabolism
Ketone Bodies
Struggling with GOB Chemistry?
Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
How is oxaloacetate related to ketone bodies formation?
A
High levels of acetyl CoA accumulate and increase the rate of citric acid cycle.
B
Oxaloacetate combines with acetyl CoA to form citrate; this leads to formation of ketone bodies.
C
Citric acid cycle is not dependent on oxaloacetate, and all acetyl CoA is free to be oxidized in the cycle.
D
Ketone bodies are formed when oxaloacetate levels are low.
E
Ketogenesis can speed up gluconeogenesis by producing more oxaloacetate.
Verified step by step guidance1
Understand the role of oxaloacetate in the citric acid cycle. Oxaloacetate is a key intermediate that combines with acetyl CoA to form citrate, which is the first step in the citric acid cycle.
Recognize the relationship between oxaloacetate levels and ketone body formation. When oxaloacetate levels are low, acetyl CoA cannot enter the citric acid cycle efficiently, leading to the accumulation of acetyl CoA.
Explore the process of ketogenesis. When acetyl CoA accumulates due to low oxaloacetate levels, the liver converts excess acetyl CoA into ketone bodies, which can be used as an alternative energy source.
Consider the impact of gluconeogenesis on oxaloacetate levels. During gluconeogenesis, oxaloacetate is used to produce glucose, which can further reduce its availability for the citric acid cycle.
Conclude that ketone bodies are formed when oxaloacetate levels are low, as the citric acid cycle is less active, and acetyl CoA is redirected towards ketogenesis.
1:29mWatch next
Master Ketone Bodies Concept 1 with a bite sized video explanation from Jules
Start learningRelated Videos
Related Practice
