Multiple Choice
Fructose-1,6-bisphosphate is dephosphorylated by ________________ to fructose-6-phosphate.
22. Carbohydrate Metabolism
Gluconeogenesis
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Enzyme responsible for decarboxylation and phosphate transfer in the same gluconeogenic reaction is:
A
Tyrosine kinase
B
Oxaloacetate carboxykinase
C
Pyruvate kinase
D
Phosphoenolpyruvate carboxykinase
E
Phosphofructokinase
Verified step by step guidance1
Understand the context of the problem: The question is asking about an enzyme involved in gluconeogenesis, specifically one that performs decarboxylation and phosphate transfer.
Identify the process: Gluconeogenesis is the metabolic pathway that results in the generation of glucose from non-carbohydrate substrates. It involves several enzymes that catalyze different reactions.
Focus on the reaction types: Decarboxylation is the removal of a carboxyl group, releasing carbon dioxide (CO2). Phosphate transfer involves the transfer of a phosphate group from one molecule to another.
Review enzyme functions: Phosphoenolpyruvate carboxykinase (PEPCK) is known for catalyzing the conversion of oxaloacetate to phosphoenolpyruvate, involving both decarboxylation and phosphate transfer.
Eliminate incorrect options: Tyrosine kinase is involved in phosphorylation of proteins, not gluconeogenesis. Pyruvate kinase is involved in glycolysis, not gluconeogenesis. Phosphofructokinase is also involved in glycolysis.
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