Multiple Choice
Which molecule is added to pyruvate and then removed in the next reaction?
22. Carbohydrate Metabolism
Gluconeogenesis
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The following metabolites are present both in glycolysis and gluconeogenesis, except:
A
oxaloacetate
B
fructose-1,6-bisphosphate
C
glyceraldehyde-3-phosphate
D
dihydroxyacetone phosphate
Verified step by step guidance1
Understand the pathways: Glycolysis is the process of breaking down glucose into pyruvate, while gluconeogenesis is the synthesis of glucose from non-carbohydrate precursors. Both pathways share some common metabolites.
Identify common metabolites: In both glycolysis and gluconeogenesis, certain intermediates are shared. These include fructose-1,6-bisphosphate, glyceraldehyde-3-phosphate, and dihydroxyacetone phosphate.
Recognize unique metabolites: Oxaloacetate is a key intermediate in gluconeogenesis but is not part of the glycolysis pathway. It is involved in the conversion of pyruvate to phosphoenolpyruvate in gluconeogenesis.
Compare the given options: List the metabolites provided in the problem and determine which are common to both pathways and which are not.
Conclude the exception: Based on the comparison, identify oxaloacetate as the metabolite that is not present in both glycolysis and gluconeogenesis, making it the correct answer to the problem.
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