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Multiple Choice
Which disaccharide forms a 1,1-glycosidic linkage?
A
Lactose
B
Maltose
C
Trehalose
D
Sucrose
E
Cellulose
Verified step by step guidance
1
Understand what a 1,1-glycosidic linkage is: It is a type of covalent bond that connects two monosaccharide units through their anomeric carbons, which are the carbon atoms that were part of the carbonyl group in the open-chain form of the sugar.
Identify the structure of each disaccharide option: Lactose, Maltose, Trehalose, Sucrose, and Cellulose. Each of these disaccharides has a unique glycosidic linkage.
Lactose is composed of glucose and galactose with a β(1→4) linkage. Maltose consists of two glucose units with an α(1→4) linkage. Sucrose is made of glucose and fructose with an α(1→2) linkage. Cellulose is a polymer of glucose with β(1→4) linkages.
Trehalose is composed of two glucose molecules connected by an α,α-1,1-glycosidic bond, meaning both anomeric carbons are involved in the linkage.
Conclude that Trehalose is the disaccharide that forms a 1,1-glycosidic linkage, as it uniquely connects two glucose units through their anomeric carbons.