Multiple Choice
Which of the following statements about calmodulin is TRUE?
12. Biosignaling
PSP Secondary Messengers & PKC
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Which of the following enzymes does diacylglycerol recruit to the membrane and activate when bound?
A
Phospholipase C.
B
Protein Kinase C.
C
Adenylate Cyclase.
D
Protein Kinase A.
E
Phospholipase A.
F
Calmodulin.
Verified step by step guidance1
Understand the role of diacylglycerol (DAG) in cell signaling. DAG is a lipid-derived second messenger that plays a crucial role in the activation of certain proteins within the cell membrane.
Identify the enzymes listed in the problem and their general functions: Phospholipase C, Adenylate Cyclase, Protein Kinase A, Protein Kinase C, Phospholipase A, and Calmodulin.
Recall that Protein Kinase C (PKC) is a family of protein kinase enzymes that are activated by DAG. PKC is involved in various cellular processes, including the regulation of growth, differentiation, and apoptosis.
Recognize that DAG remains in the membrane after its formation and serves as a docking site for PKC, facilitating its activation.
Conclude that among the given options, Protein Kinase C is the enzyme that is recruited to the membrane and activated by diacylglycerol.
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