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Multiple Choice
Protein Kinase C (PKC) is activated when bound by:
A
Ca2+ which leads to cytosolic protein phosphorylation.
B
Diacylglycerol which leads to cytosolic protein phosphorylation.
C
Ca2+ and Diacylglycerol which leads to extracellular protein phosphorylation.
D
Ca2+ and Diacylglycerol which leads to cytosolic protein phosphorylation.
E
Diacylglycerol which leads to extracellular protein phosphorylation.
Verified step by step guidance
1
Understand the role of Protein Kinase C (PKC): PKC is an enzyme that plays a role in several cellular processes by phosphorylating proteins. It is activated by certain molecules, leading to protein phosphorylation.
Identify the activators of PKC: PKC is typically activated by calcium ions (Ca2+) and diacylglycerol (DAG). These molecules bind to PKC and facilitate its activation.
Determine the location of phosphorylation: PKC, when activated by Ca2+ and DAG, usually phosphorylates proteins in the cytosol, not extracellularly.
Evaluate the given options: Analyze each option to see which combination of activators and phosphorylation location matches the typical behavior of PKC.
Select the correct answer: Based on the understanding that PKC is activated by Ca2+ and DAG leading to cytosolic protein phosphorylation, identify the correct statement from the options provided.