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Multiple Choice
The reaction catalyzed by Phospholipase C can use all of the following EXCEPT:
A
Phosphatidylinositol bisphosphate as a substrate.
B
Diacylglycerol as a product.
C
Diacylglycerol phosphate as a product.
D
Inositol triphosphate as a product.
E
Water as a substrate.
Verified step by step guidance
1
Understand the role of Phospholipase C: Phospholipase C is an enzyme that plays a crucial role in cell signaling by hydrolyzing phosphatidylinositol bisphosphate (PIP2) into two important secondary messengers.
Identify the substrates and products: Phospholipase C uses phosphatidylinositol bisphosphate (PIP2) and water as substrates. The enzyme catalyzes the reaction to produce inositol triphosphate (IP3) and diacylglycerol (DAG) as products.
Clarify the exception: The problem states that diacylglycerol phosphate is listed as a product, which is incorrect. Phospholipase C does not produce diacylglycerol phosphate; it produces diacylglycerol (DAG) instead.
Review the chemical reaction: The reaction can be represented as: . This equation shows the substrates and products involved in the reaction catalyzed by Phospholipase C.
Conclude with the correct answer: Based on the understanding of the reaction, diacylglycerol phosphate is not a product of the reaction catalyzed by Phospholipase C, making it the correct answer to the problem.