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Multiple Choice
ABC transporters are a part of a superfamily of transporters that have two nucleotide binding domains that bind __________, which is necessary for primary active transport.
A
ADP.
B
Phosphate.
C
ATP.
D
GTP.
E
AMP.
Verified step by step guidance
1
Understand the role of ABC transporters: ABC (ATP-Binding Cassette) transporters are a large family of proteins that utilize the energy from ATP hydrolysis to transport various molecules across cellular membranes.
Identify the key components of ABC transporters: They have two nucleotide-binding domains (NBDs) that are crucial for their function.
Recognize the energy source for ABC transporters: These transporters use the energy derived from the hydrolysis of ATP (adenosine triphosphate) to drive the transport process.
Differentiate between the nucleotide options: ATP is the primary molecule that provides energy for active transport, as it releases energy upon hydrolysis to ADP (adenosine diphosphate) and inorganic phosphate.
Conclude the correct answer: Based on the function of ABC transporters and the role of ATP in providing energy, the correct nucleotide that binds to the nucleotide-binding domains is ATP.