Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

11. Biological Membranes and Transport

SERCA: Calcium Ion Pump

Biochemistry

11. Biological Membranes and Transport

SERCA: Calcium Ion Pump

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Multiple Choice

The calcium ATPase (SERCA) _____________________:

Is a V-type ATPase that transports calcium inside vesicles.

Is a P-type ATPase that maintains cytosolic [Ca²⁺] around 0.1 μM & sarcoplasmic reticulum [Ca²⁺] at 1.5 mM.

Is a P-type ATPase and an example of passive facilitated diffusion.

Is a P-type ATPase that transports calcium from the ER to the cytoplasm.

None of the above are true.

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Verified step by step guidance

Understand the role of calcium ATPase (SERCA) in cellular processes. SERCA is responsible for transporting calcium ions (Ca2+) from the cytosol into the sarcoplasmic reticulum, a type of endoplasmic reticulum in muscle cells.

Identify the type of ATPase that SERCA belongs to. SERCA is a P-type ATPase, which means it uses the energy from ATP hydrolysis to transport ions across membranes, creating a concentration gradient.

Recognize the function of SERCA in maintaining calcium ion concentrations. It keeps cytosolic calcium concentration low (around 0.1 μM) and sarcoplasmic reticulum calcium concentration high (around 1.5 mM).

Differentiate between active transport and passive facilitated diffusion. SERCA performs active transport, not passive facilitated diffusion, as it moves calcium ions against their concentration gradient using energy from ATP.

Evaluate the given options based on the understanding of SERCA's function and type. The correct statement is that SERCA is a P-type ATPase that maintains cytosolic [Ca2+] around 0.1 μM and sarcoplasmic reticulum [Ca2+] at 1.5 mM.