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Multiple Choice
Non-steroidal anti-inflammatory drugs (NSAIDS), like aspirin & ibuprofen, lower body temperatures by blocking production of which eicosanoid? A) Biological waxes. B) Prostaglandins. C) Sphingolipids. D) Vitamin D. E) Cholesterol & other isoprenoids.
A
Biological waxes.
B
Prostaglandins.
C
Sphingolipids.
D
Vitamin D.
E
Cholesterol & other isoprenoids.
Verified step by step guidance
1
Understand the role of NSAIDs: Non-steroidal anti-inflammatory drugs (NSAIDs) are medications that reduce inflammation, pain, and fever. They achieve this by inhibiting certain enzymes involved in the inflammatory process.
Identify the target of NSAIDs: NSAIDs primarily target the cyclooxygenase (COX) enzymes, which are crucial for the conversion of arachidonic acid into eicosanoids, including prostaglandins.
Learn about prostaglandins: Prostaglandins are a group of physiologically active lipid compounds having diverse hormone-like effects in animals. They are derived from fatty acids and play a key role in inflammation and fever regulation.
Connect the inhibition to the effect: By blocking the COX enzymes, NSAIDs prevent the synthesis of prostaglandins. This reduction in prostaglandin levels leads to decreased inflammation and lower body temperature.
Review the options: Among the given options, prostaglandins are the eicosanoids whose production is blocked by NSAIDs, leading to the lowering of body temperature.