Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

4. Protein Structure

Antiparallel and Parallel Beta Sheets

Biochemistry

4. Protein Structure

Antiparallel and Parallel Beta Sheets

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Multiple Choice

The major reason that antiparallel β-sheets are more stable than parallel β-sheets is that the latter:

Are in a slightly less extended configuration than antiparallel strands.

Do not have as many disulfide crosslinks between adjacent strands.

Do not stack in sheets as well as antiparallel strands.

Have fewer lateral hydrogen bonds than antiparallel strands.

Have weaker hydrogen bonds laterally between adjacent strands.

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Verified step by step guidance

Understand the structure of β-sheets: β-sheets are a type of secondary structure in proteins, consisting of β-strands connected laterally by at least two or three backbone hydrogen bonds, forming a generally twisted, pleated sheet.

Differentiate between antiparallel and parallel β-sheets: In antiparallel β-sheets, the N-terminus to C-terminus direction of adjacent strands is opposite, while in parallel β-sheets, the strands run in the same direction.

Analyze hydrogen bonding in β-sheets: In antiparallel β-sheets, the hydrogen bonds between the strands are more linear and thus stronger, compared to the less linear and weaker hydrogen bonds in parallel β-sheets.

Consider the impact of hydrogen bond strength on stability: Stronger hydrogen bonds in antiparallel β-sheets contribute to greater stability compared to the weaker hydrogen bonds in parallel β-sheets.

Conclude why antiparallel β-sheets are more stable: The key reason for the increased stability of antiparallel β-sheets is the stronger, more linear hydrogen bonds between adjacent strands, making them more stable than parallel β-sheets.