Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

7. Enzyme Inhibition and Regulation

Allosteric Effectors

Biochemistry

7. Enzyme Inhibition and Regulation

Allosteric Effectors

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Multiple Choice

Which of the following statements about allosteric control of enzymatic activity is false?

Allosteric effectors give rise to sigmoidal V₀ vs. [S] kinetic plots.

Allosteric proteins are generally composed of several subunits.

An allosteric effector may either inhibit or activate an enzyme.

Binding of the allosteric effector to the enzyme changes the conformation of the enzyme.

Heterotropic allosteric effectors compete with the substrate for binding sites on the enzyme.

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Verified step by step guidance

Understand the concept of allosteric control: Allosteric control involves the regulation of an enzyme's activity through the binding of molecules called allosteric effectors at sites other than the active site. This binding can alter the enzyme's conformation and activity.

Review the characteristics of allosteric enzymes: Allosteric enzymes often have multiple subunits and exhibit cooperative binding, which can lead to sigmoidal kinetic plots when plotting initial velocity (V0) against substrate concentration ([S]).

Differentiate between homotropic and heterotropic effectors: Homotropic effectors are typically the substrate itself, while heterotropic effectors are different molecules that bind to the enzyme and modulate its activity.

Examine the statement about heterotropic effectors: Heterotropic allosteric effectors do not compete with the substrate for binding at the active site; instead, they bind at distinct allosteric sites, influencing enzyme activity indirectly.

Identify the false statement: The statement claiming that heterotropic allosteric effectors compete with the substrate for binding sites is incorrect, as they bind at separate allosteric sites, not the active site.