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Multiple Choice
Is there a difference between oncogenes and tumor suppressor genes?
A
Yes, oncogenes are genes that can cause cancer when they become mutated to become proto-oncogenes, whereas tumor suppressor genes play no role in cancer.
B
Yes, oncogenes prevent cancer from forming unless they are mutated to become proto-oncogenes, whereas tumor suppressor genes stimulate the formation of cancer even in the absence of mutation.
C
No, oncogenes and tumor suppressor genes both stimulate the development of cancer, even in the absence of their becoming mutated.
D
Yes, oncogenes are mutated versions of genes that promote abnormal cell division (such as mutated Ras), whereas tumor suppressor genes are genes that normally inhibit cell division.
E
No, since both types of genes contribute to the development of cancer, there is no difference between them.
Verified step by step guidance
1
Understand the role of oncogenes: Oncogenes are mutated forms of normal genes called proto-oncogenes. Proto-oncogenes typically promote cell growth and division. When mutated, they become oncogenes, which can lead to uncontrolled cell division and contribute to cancer development.
Understand the role of tumor suppressor genes: Tumor suppressor genes are involved in regulating cell division and ensuring cells do not divide uncontrollably. They act as a brake on cell division, and when they are mutated or inactivated, this control is lost, potentially leading to cancer.
Differentiate between oncogenes and tumor suppressor genes: Oncogenes result from the activation (gain of function) of proto-oncogenes, leading to excessive cell division. In contrast, tumor suppressor genes contribute to cancer when they are inactivated (loss of function), removing the inhibition on cell division.
Analyze the given options: The correct statement should reflect the roles of oncogenes and tumor suppressor genes as described. Oncogenes are mutated versions of genes that promote abnormal cell division, while tumor suppressor genes normally inhibit cell division.
Select the correct answer: Based on the understanding of the roles of oncogenes and tumor suppressor genes, choose the option that accurately describes their functions and differences in the context of cancer development.