Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

12. Biosignaling

Signaling Defects & Cancer

Biochemistry

12. Biosignaling

Signaling Defects & Cancer

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Multiple Choice

The protein product of the Ras oncogene is a mutated Ras protein. All of the following would be true EXCEPT:

The Ras protein is a G-protein and functions as an internal clock.

G-proteins have evolved to stay active for a certain length of time.

Ras protein is active in cell growth and division.

Ras can mutate so that it is less active as a GTPase.

A less active GTPase would mean less stimulation of the MAP kinase pathway.

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Verified step by step guidance

Understand the role of Ras protein: Ras is a G-protein involved in cell signaling, particularly in pathways that regulate cell growth and division.

Recognize the function of G-proteins: G-proteins act as molecular switches inside cells, and they are active when bound to GTP and inactive when bound to GDP.

Identify the role of GTPase activity: Ras has intrinsic GTPase activity, which allows it to hydrolyze GTP to GDP, turning itself off. This activity is crucial for regulating the duration of the signal.

Consider the impact of mutations: Mutations in Ras can affect its GTPase activity. A mutation that reduces GTPase activity would result in Ras being active for longer periods, potentially leading to uncontrolled cell growth.

Evaluate the exception statement: The statement 'A less active GTPase would mean less stimulation of the MAP kinase pathway' is incorrect because a less active GTPase would actually lead to prolonged activation of the MAP kinase pathway, not less stimulation.