Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

What can the binding energy (ΔG_B) of an enzyme catalyzed reaction tell us?

The change in the rate/speed of the reaction.

The change in the equilibrium constant (K_eq) of the reaction.

The change in the reaction E_A between the catalyzed & uncatalyzed transition states.

a & c.

All options are true.

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Verified step by step guidance

Understand that binding energy (ΔG_B) refers to the energy released when an enzyme binds to its substrate, stabilizing the transition state and lowering the activation energy (E_A).

Recognize that a decrease in activation energy (E_A) due to enzyme binding increases the rate of the reaction, as per the Arrhenius equation, which relates reaction rate to activation energy.

Note that the equilibrium constant (K_eq) of a reaction is determined by the difference in free energy between reactants and products, not by the activation energy or binding energy. Therefore, ΔG_B does not directly affect K_eq.

Identify that the binding energy (ΔG_B) affects the transition state by lowering the activation energy (E_A) for the catalyzed reaction compared to the uncatalyzed reaction, thus facilitating the reaction.

Conclude that the binding energy (ΔG_B) is related to both the change in reaction rate (option a) and the change in activation energy between catalyzed and uncatalyzed states (option c), but not directly to the equilibrium constant (K_eq).