Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

4. Protein Structure

Denaturation

Biochemistry

4. Protein Structure

Denaturation

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Multiple Choice

Which of the following is likely not affected if the pH of a protein solution is suddenly altered to 12?

Amino acid composition.

α-helices.

Motifs.

R-group interactions.

β-sheets.

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Verified step by step guidance

Understand the impact of pH on protein structure: Proteins are sensitive to changes in pH, which can affect their structure and function. At a high pH of 12, the environment is highly basic, which can lead to deprotonation of certain groups within the protein.

Consider the role of R-group interactions: The R-groups (side chains) of amino acids can be affected by changes in pH, as they may gain or lose protons, altering their charge and interactions. This can impact the protein's tertiary structure.

Examine secondary structures like α-helices and β-sheets: These structures are stabilized by hydrogen bonds, which can be disrupted by changes in pH, potentially leading to denaturation or alteration of the protein's shape.

Evaluate motifs: Motifs are specific arrangements of secondary structures that contribute to the protein's overall shape and function. Changes in pH can affect the stability of these motifs by altering hydrogen bonding and ionic interactions.

Assess amino acid composition: The amino acid composition refers to the sequence of amino acids in the protein, which is determined by the genetic code and is not affected by changes in pH. Therefore, the amino acid composition remains unchanged even if the pH is altered.