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Multiple Choice
Use the image of the following glucose molecule to answer the questions. A) Upon cyclization, which of the red circled carbons becomes the anomeric carbon? a) A. b) B. c) C. d) D. e) E. B) Upon cyclization, would a hemiacetal or hemiketal form?
A
A
B
B
C
C
D
D
E
E
Verified step by step guidance
1
Identify the structure of glucose: Glucose is an aldohexose, meaning it has an aldehyde group and six carbon atoms.
Understand cyclization: In aqueous solutions, glucose can cyclize to form a ring structure. This involves the reaction between the aldehyde group and one of the hydroxyl groups.
Determine the anomeric carbon: The anomeric carbon is the carbon that was part of the carbonyl group (aldehyde or ketone) before cyclization. In glucose, this is the carbon that forms the new chiral center during ring formation.
Analyze the image: In the provided image, the carbon labeled 'E' is the one that has the double-bonded oxygen, indicating it is the carbonyl carbon. Upon cyclization, this carbon becomes the anomeric carbon.
Classify the type of cyclic structure: Since glucose is an aldose, the cyclization forms a hemiacetal. A hemiacetal is formed when an aldehyde reacts with an alcohol group.