Multiple Choice
Which of the following reactions does the enzyme adenylate cyclase catalyze?
12. Biosignaling
Stimulatory Adenylate Cyclase GPCR Signaling
Multiple Choice
Which of the following molecules is NOT involved in signal transduction of the β-adrenergic GPCR?
A
GTP.
B
ATP.
C
cAMP.
D
cGMP.
E
GDP.
Verified step by step guidance1
Understand the role of β-adrenergic GPCRs: These are G protein-coupled receptors that, when activated by ligands such as adrenaline, initiate a signaling cascade inside the cell.
Identify the key molecules involved in the β-adrenergic GPCR signaling pathway: Typically, this involves the activation of a G protein, which exchanges GDP for GTP, and the production of cAMP from ATP by adenylyl cyclase.
Recognize the role of GTP and GDP: GTP is used to activate the G protein, while GDP is released when the G protein is inactivated.
Understand the role of ATP and cAMP: ATP is converted to cAMP, which acts as a secondary messenger to propagate the signal within the cell.
Identify cGMP: cGMP is a cyclic nucleotide similar to cAMP but is not typically involved in the β-adrenergic GPCR signaling pathway, making it the correct answer as the molecule not involved in this specific pathway.
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