Multiple Choice
Which of the following defines the type of transport by the sodium-potassium ATPase?
11. Biological Membranes and Transport
Sodium-Potassium Ion Pump
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Which of the following statements about the mechanism of the sodium-potassium ATPase is FALSE?
A
It helps to create a transmembrane potential that is more negative on the inside and more positive on the outside.
B
It pumps 3 Na+ ions out of the cell.
C
It pumps 2 K+ ions into the cell.
D
The ATPase is phosphorylated by ATP to transport of Na+ into the cell.
E
All of the statements above are correct.
Verified step by step guidance1
Understand the function of sodium-potassium ATPase: It is an enzyme that helps maintain the electrochemical gradient across the cell membrane by actively transporting sodium (Na⁺) and potassium (K⁺) ions against their concentration gradients.
Review the typical mechanism of sodium-potassium ATPase: The enzyme pumps 3 Na⁺ ions out of the cell and 2 K⁺ ions into the cell, using energy from ATP hydrolysis.
Consider the role of ATP in the mechanism: ATP phosphorylates the ATPase, causing a conformational change that allows the transport of Na⁺ ions out of the cell, not into the cell.
Evaluate the statement about transmembrane potential: The activity of the ATPase contributes to a more negative charge inside the cell and a more positive charge outside, which is consistent with the function of the pump.
Identify the false statement: The statement that the ATPase is phosphorylated by ATP to transport Na⁺ into the cell is incorrect, as phosphorylation facilitates the transport of Na⁺ out of the cell.
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