Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

7. Enzyme Inhibition and Regulation

Zymogens

Biochemistry

7. Enzyme Inhibition and Regulation

Zymogens

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Multiple Choice

Why are most digestive enzymes produced as zymogens?

To prevent digestion of cellular enzymes that would destroy the cell.

So that the inactive enzyme can be transported in the bloodstream.

Because the zymogen has a higher affinity for its substrate.

Because the zymogen can't be post-translationally modified.

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Verified step by step guidance

Understand the concept of zymogens: Zymogens are inactive precursors of enzymes. They require a biochemical change to become active enzymes. This change often involves the cleavage of specific peptide bonds.

Consider the role of digestive enzymes: Digestive enzymes are responsible for breaking down food molecules into smaller components. If these enzymes were active within the cells where they are produced, they could potentially digest cellular components, leading to cell damage or death.

Explore the mechanism of zymogen activation: Zymogens are activated in specific locations, such as the digestive tract, where they perform their function without harming the cells that produce them. This spatial regulation is crucial for cellular protection.

Evaluate the transport and activation of zymogens: Zymogens can be safely transported to their site of action in an inactive form, preventing premature activity. Once they reach the appropriate location, they are activated by specific factors or conditions.

Conclude why zymogens are produced: The production of enzymes as zymogens is a protective mechanism to prevent the enzymes from digesting the cells that produce them. This ensures that the enzymes are only active where and when they are needed, safeguarding cellular integrity.